Glas was accused of accepting US$ 16 million in bribes from Odebrecht – a company that was charged with paying Latin American business leaders and government officials millions in illegal kickbacks to win public contracts.
Senior members of former President Rafael Correa’s government allegedly brought forward the accusations against Glas. He served as a minister and vice president for seven years in Correa’s government.
Ecuadoran lawmakers in August decided to allow the corruption probe against Glas to proceed.
He has denied any wrongdoing and claims that the court’s ruling is a politicized campaign against him.
"Don't worry, you don't have to search for me, I'm where I always am," Glas said on Twitter. "I'm not going to escape. Those who are innocent never flee."
Glas is already barred from leaving Ecuador and the pre-trial detention is meant to prevent him from fleeing the country during the ongoing investigation.
In August, Ecuardorian president Lenin Moreno discharged Glas from all his duties as vice president following a dispute, and relegated him to a mainly ceremonial role.
Odebrecht was charged with paying about US$ 788 million in bribes in 12 countries in Central and South America and in Africa to win contracts between 2001 to 2016.
The scandal has led to the arrest of dozens of business leaders and public officials.